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Lactated Ringer's solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized,

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Presentation on theme: "Lactated Ringer's solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized,"— Presentation transcript:

1 Lactated Ringer's solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized, double-blinded, placebo-controlled trial  Shaffer R.S. Mok, MD, MBS, Henry C. Ho, MD, Paurush Shah, MD, Milan Patel, MD, John P. Gaughan, MS, PhD, MBA, Adam B. Elfant, MD, FACG  Gastrointestinal Endoscopy  Volume 85, Issue 5, Pages (May 2017) DOI: /j.gie Copyright © 2017 American Society for Gastrointestinal Endoscopy Terms and Conditions

2 Figure 1 Flow diagram with enrollment and outcomes. NSAID, nonsteroidal anti-inflammatory drug; CKD, chronic kidney disease; CHF, congestive heart failure; PUD, peptic ulcer disease; ARF, acute renal failure; NS, normal saline solution; IND, indomethacin; LR, lactated Ringer's solution. Gastrointestinal Endoscopy  , DOI: ( /j.gie ) Copyright © 2017 American Society for Gastrointestinal Endoscopy Terms and Conditions

3 Figure 2 The incidence of the primary outcome of post-ERCP pancreatitis. Bars from left to right indicate NS + placebo (Pl), NS + IND, LR + Pl, and LR + IND groups. The difference between the NS + Pl versus LR + IND group was significant (P = .04). ns, Not significant; NS, normal saline solution; IND, indomethicin; LR, lactated Ringer's solution; Pl, placebo; PEP, post-ERCP pancreatitis. Gastrointestinal Endoscopy  , DOI: ( /j.gie ) Copyright © 2017 American Society for Gastrointestinal Endoscopy Terms and Conditions

4 Figure 3 The incidence of secondary outcome readmission rates. Bars from left to right indicate NS + placebo (Pl), NS + IND, LR + Pl, and LR + IND groups. The difference between the NS + Pl versus LR+IND group was significant (P = .03). ns, Not significant; NS, normal saline solution; IND, indomethicin; LR, lactated Ringer's solution; Pl, placebo. Gastrointestinal Endoscopy  , DOI: ( /j.gie ) Copyright © 2017 American Society for Gastrointestinal Endoscopy Terms and Conditions


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