1. Nat. Rev. Neurol. doi:10.1038/nrneurol.2016.152
Figure 2 Estimated lead times and diagnostic strengths of prodromal PD markers
Figure 2 | Estimated lead times and diagnostic strengths of prodromal PD markers. The prodromal and risk markers included in the International Parkinson and Movement Disorders Society task force criteria for prodromal PD are shown. Lead times are illustrated by the lengths of arrows (excluding blue boxes), and diagnostic strengths are indicated by the height on the vertical axis. All estimates of lead times are notably imprecise, but the dashed arrows indicate lead time estimates that are particularly uncertain because attempts to directly estimate them have not been made. LR+, positive likelihood ratio; REM, rapid eye movement; SPECT, single-photon emission CT.
Postuma, R. B. & Berg, D. (2016) Advances in markers of prodromal Parkinson disease
Nat. Rev. Neurol. doi: /nrneurol