1. Volume 41, Issue 5, Pages 453-454 (June 2017)
At the Crossroads between Cell Polarity and Adhesion in Neocortical Development 
Sergei Y. Sokol 
Developmental Cell 
Volume 41, Issue 5, Pages (June 2017)
DOI: /j.devcel
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2. Figure 1
N-Cadherin Is Stabilized at Apical Cell Junctions by Lgl1 and aPKC
Protein interactions in the apical-lateral corner of a V/SVZ neuroepithelial progenitor are shown. The binding of N-cadherin by Lgl1 along the basolateral surface of the radial glial progenitor results in N-cadherin internalization (red arrow); however, aPKC antagonizes this interaction by phosphorylating Lgl1 at cell junctions, leading to selective junctional accumulation of N-cadherin in normal embryos. In Lgl1 mutant tissues, N-cadherin accumulates throughout the basolateral surface, causing disorganization of the AJC.
Developmental Cell  , DOI: ( /j.devcel )
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