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Spermatogonial survival in long-term human prepubertal xenografts

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Presentation on theme: "Spermatogonial survival in long-term human prepubertal xenografts"— Presentation transcript:

1 Spermatogonial survival in long-term human prepubertal xenografts
Ellen Goossens, Ph.D., Mieke Geens, M.Sc., Gert De Block, Herman Tournaye, M.D., Ph.D.  Fertility and Sterility  Volume 90, Issue 5, Pages (November 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Human prepubertal testicular tissue grafted on the backs of immunodeficient mice. (A, C, E) MAGE-A4–positive cells: spermatogonia. (B, D, F) Vimentin-positive cells: Sertoli cells. (A, B) Immature human testis tissue before grafting. The tubules contain Sertoli cells and spermatogonia. (C, D) Testicular tissue 4 months after grafting. (E, F) Testicular tissue 9 months after grafting. Spermatogonia remain in some seminiferous tubules. Bar = 70 μm. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


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