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Figure 2 Examples of lesions with and without central veins

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1 Figure 2 Examples of lesions with and without central veins
Figure 2 | Examples of lesions with and without central veins. The lesions are classified as harbouring a central vein (parts a–c), not harbouring a central vein (parts d–f), or excluded from analysis (parts g–i). FLAIR* (combined T2*-weighted MRI and fluid-attenuated inversion recovery) images were collected at 3 T from the NIH multiple sclerosis cohort, and were reformatted in all three planes (axial, coronal and sagittal). The relevant lesions are indicated by arrowheads in each case. a | Dawson's finger-shaped lesion with a central vein running perpendicular to the sagittal plane. b | Periventricular lesion with a hypointense rim located next to the atrium of the lateral ventricle. c | Small finger-like lesion with a diameter slightly >3 mm in its short axis. The central vein is not as conspicuous as in previous examples, but it is still visible. d | Small deep white matter lesion with diameter >3 mm and no visible central vein in any plane. e | Small subcortical lesion with diameter >3 mm and no visible central vein in any plane. f | Juxtacortical lesion with no visible central vein in any plane. g | Small hyperintense area with diameter <3 mm located around a parenchymal vein. h | Periventricular lesion with branching veins. i | Confluent lesions with multiple veins. Sati, P. et al. (2016) The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative Nat. Rev. Neurol. doi: /nrneurol

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