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Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine  Renske van Delft, Danielle Lambrechts,

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Presentation on theme: "Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine  Renske van Delft, Danielle Lambrechts,"— Presentation transcript:

1 Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine  Renske van Delft, Danielle Lambrechts, Pauline Verschuure, Jacques Hulsman, Marian Majoie  Seizure - European Journal of Epilepsy  Volume 19, Issue 1, Pages (January 2010) DOI: /j.seizure Copyright © 2009 British Epilepsy Association Terms and Conditions

2 Fig. 1 Ketone formation. Ketones are formed when acetyl-CoA is not able to enter the Krebs Cycle. Seizure - European Journal of Epilepsy  , 36-39DOI: ( /j.seizure ) Copyright © 2009 British Epilepsy Association Terms and Conditions

3 Fig. 2 BHB concentration related to reduction at 3 months.
Seizure - European Journal of Epilepsy  , 36-39DOI: ( /j.seizure ) Copyright © 2009 British Epilepsy Association Terms and Conditions

4 Fig. 3 BHB concentration related to reduction at 6 months.
Seizure - European Journal of Epilepsy  , 36-39DOI: ( /j.seizure ) Copyright © 2009 British Epilepsy Association Terms and Conditions

5 Fig. 4 Ketones in urine (average) related to reduction at 3 months. Spearman rank: R=0.10, p=0.32. Seizure - European Journal of Epilepsy  , 36-39DOI: ( /j.seizure ) Copyright © 2009 British Epilepsy Association Terms and Conditions

6 Fig. 5 Ketones in urine (average) related to reduction at 6 months. Spearman rank: R=0.09, p=0.36. Seizure - European Journal of Epilepsy  , 36-39DOI: ( /j.seizure ) Copyright © 2009 British Epilepsy Association Terms and Conditions


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