1. Should we irradiate a brain tumor in a patient with parkinsonism
Should we irradiate a brain tumor in a patient with parkinsonism? A case report and literature review 
Alexander Engelman, MD, MS, Karthikeyan Perumal, MBBS, Minesh Mehta, MBChB 
Practical Radiation Oncology 
Volume 5, Issue 4, Pages e327-e335 (July 2015)
DOI: /j.prro
Copyright © 2015 American Society for Radiation Oncology Terms and Conditions

2. Figure 1
Relative risk of brain tumor among patients with Parkinson’s disease.5-8
Practical Radiation Oncology 2015 5, e327-e335DOI: ( /j.prro )
Copyright © 2015 American Society for Radiation Oncology Terms and Conditions

3. Figure 2
Axial T2 magnetic resonance images (MRIs) of the brain from a 16-month-old child who received 55 Gy posterior fossa radiation therapy for a recurrent medulloblastoma. (A) T2-weighted MRI 1 month after completion of radiation therapy showing normal basal ganglia appearance. (B) T2-weighted MRI 7 months after radiation therapy showing high signal changes in the basal ganglia (arrow). (C) T2-weighted MRI showing residual changes in the basal ganglia 4 years after initial onset of parkinsonism (arrow). Reproduced with permission from Skiming et al.16
Practical Radiation Oncology 2015 5, e327-e335DOI: ( /j.prro )
Copyright © 2015 American Society for Radiation Oncology Terms and Conditions

4. Figure 3
Images from a 16-year-old who received 54 Gy for a craniopharyngioma. (A) Axial computed tomography image with treatment volumes and isodose lines; prescription isodoses of 54 Gy. Inner black circle represents the gross tumor volume; outer black circle, planning target volume. (B) T2-weighted magnetic resonance image 9 months after radiation therapy and 2 months after parkinsonism onset showing high signal intensity of the globus pallidus and no increase in tumor. Reproduced with permission from Voermans et al.23
Practical Radiation Oncology 2015 5, e327-e335DOI: ( /j.prro )
Copyright © 2015 American Society for Radiation Oncology Terms and Conditions