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Differential in vitro activity of anidulafungin, caspofungin and micafungin against Candida parapsilosis isolates recovered from a burn unit M.A. Ghannoum, A. Chen, M. Buhari, J. Chandra, P.K. Mukherjee, D. Baxa, A. Golembieski, J.A. Vazquez Clinical Microbiology and Infection Volume 15, Issue 3, Pages (March 2009) DOI: /j x Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions
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FIG. 1 Electrophoretic karyotype of Candida parapsilosis isolates recovered from eight different patients. Lanes A and B: controls. Lanes C–J: patient isolates. Clinical Microbiology and Infection , DOI: ( /j x) Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions
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FIG. 2 Effect of anidulafungin (ANID) and caspofungin (CASPO) on surface structure and morphology of (a—c) caspofungin-susceptible or (d–f) caspofungin-non-susceptible C. parapsilosis isolates. The susceptible C. parapsilosis isolate was exposed to: (a) no drug (control); (b) anidulafungin, 0.25 mg/L; or (c) caspofungin, 0.25 mg/L. The non-susceptible C. parapsilosis isolate was exposed to: (d) no drug; (e) anidulafungin, 2 mg/L; or (f) caspofungin, 16 mg/L. Bars represent 5 üm in (a)-(e) and 10 üm in (f). Magnification: ×8000 (a), and x5000 (b–f). Clinical Microbiology and Infection , DOI: ( /j x) Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions
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