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Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation With Conformal External Beam Radiotherapy or Single-Entry.

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Presentation on theme: "Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation With Conformal External Beam Radiotherapy or Single-Entry."— Presentation transcript:

1 Prospective Comparison of Toxicity and Cosmetic Outcome After Accelerated Partial Breast Irradiation With Conformal External Beam Radiotherapy or Single-Entry Multilumen Intracavitary Brachytherapy  Shane R. Stecklein, MD, PhD, Simona F. Shaitelman, MD, EdM, Gildy V. Babiera, MD, Isabelle Bedrosian, MD, Dalliah M. Black, MD, Matthew T. Ballo, MD, Isadora Arzu, MD, PhD, Eric A. Strom, MD, Valerie K. Reed, MD, Tomas Dvorak, MD, Benjamin D. Smith, MD, Wendy A. Woodward, MD, PhD, Karen E. Hoffman, MD, MHSc, MPH, Pamela J. Schlembach, MD, Steve M. Kirsner, MS, Christopher L. Nelson, PhD, Jinzhong Yang, PhD, William Guerra, BA, Shiva Dibaj, PhD, Elizabeth S. Bloom, MD  Practical Radiation Oncology  Volume 9, Issue 1, Pages e4-e13 (January 2019) DOI: /j.prro Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

2 Figure 1 (A) Actuarial incidence of fair or poor cosmetic outcome at any point during observation period for brachytherapy accelerated partial breast irradiation (APBI) and 3-dimensional conformal radiation therapy (CRT) APBI patients. Statistic is log-rank. Numbers below indicate number remaining at risk at each time point. (B) Trends in cosmetic outcome over time. All patients and observations are displayed; each dot denotes a separate observation. P is the effect of treatment (3-dimensional CRT vs brachytherapy), and P is the effect of time. (C) Effect of bra cup size on worst cosmetic score in brachytherapy APBI patients. Practical Radiation Oncology 2019 9, e4-e13DOI: ( /j.prro ) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

3 Figure 2 Actuarial incidence curves of fair or poor cosmesis in brachytherapy accelerated partial breast irradiation patients using the identified threshold values (inlays). Statistic is log-rank. Practical Radiation Oncology 2019 9, e4-e13DOI: ( /j.prro ) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

4 Supplemental Figure 1 Practical Radiation Oncology 2019 9, e4-e13DOI: ( /j.prro ) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

5 Supplemental Figure 2 Practical Radiation Oncology 2019 9, e4-e13DOI: ( /j.prro ) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

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