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Driving Ability Under Long-Term Treatment with Transdermal Fentanyl

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1 Driving Ability Under Long-Term Treatment with Transdermal Fentanyl
Rainer Sabatowski, MD, Susanne Schwalen, MD, Klaus Rettig, MS, Klaus W Herberg, MD, Stephan M Kasper, MD, Lukas Radbruch, MD  Journal of Pain and Symptom Management  Volume 25, Issue 1, Pages (January 2003) DOI: /S (02)

2 Fig. 1 TAVT score. The number of mistakes in the testing of tachistoscopic perception showing significant non-inferiority in the intent-to-treat (ITT) group as well as in the per-protocol-group (PP) compared to the control group (ITT: P = 0.004; PP: P = 0.003). Results of the control group are shown as raw values. Journal of Pain and Symptom Management  , 38-47DOI: ( /S (02) )

3 Fig. 2 Sum score. Sum score of the z-transformed DT, COG, and TAVT, representing the cognitive items of the test battery. The PP-group was shown to be significantly non-inferior to the control group (P = 0.036); the ITT group did not differ significantly from the control group (P = 0.188). The full circles represent the mean score plus the calculated delta as described in the method section. The values of the control group of the ITT- and the PP-group differ due to the different samples used in the z-transformation. Journal of Pain and Symptom Management  , 38-47DOI: ( /S (02) )

4 Fig. 3 Percentage of passed tests. The percentage of patients who passed the five tests (i.e., scored above the 16th percentile) showed no difference between the ITT-, PP- and control groups (ITT-group: n = 30 in DT, COG and TAVT; n = 29 in 2-Hand and VIG; PP-group: n = 21 in DT, COG and TAVT; n = 20 in 2-Hand and VIG; Control-group: n = 90 in all tests). Journal of Pain and Symptom Management  , 38-47DOI: ( /S (02) )


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