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Impact of Biochemical Failure After Salvage Radiation Therapy on Prostate Cancer– specific Mortality: Competition Between Age and Time to Biochemical Failure William C. Jackson, Krithika Suresh, Vasu Tumati, Robert T. Dess, Payal D. Soni, Shuang G. Zhao, Zachary S. Zumsteg, Raquibul Hannan, Brent K. Hollenbeck, Arvin George, Samuel D. Kaffenberger, Simpa S. Salami, Jason W.D. Hearn, Todd M. Morgan, Rohit Mehra, Matthew Schipper, Felix Y. Feng, Neil B. Desai, Daniel E. Spratt European Urology Oncology Volume 1, Issue 4, Pages (September 2018) DOI: /j.euo Copyright © 2018 European Association of Urology Terms and Conditions
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Fig. 1 Waterfall plot of time to biochemical recurrence (BCR) for all men who experienced BCR of prostate cancer after salvage radiotherapy (n=247). European Urology Oncology 2018 1, DOI: ( /j.euo ) Copyright © 2018 European Association of Urology Terms and Conditions
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Fig. 2 Plot of average hazard of distant metastasis (DM) within 5 yr after biochemical recurrence (BCR) of prostate cancer. Computed as (number of DM events within 5 yr)/(person-years of follow-up within 5 yr). SRT=salvage radiotherapy. European Urology Oncology 2018 1, DOI: ( /j.euo ) Copyright © 2018 European Association of Urology Terms and Conditions
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Fig. 3 Results for the c-index and hazard ratio with 95% confidence interval from landmark Cox models of biochemical recurrence at 6, 12, 18, and 24 mo after salvage radiotherapy (SRT) adjusted for baseline covariates for the distant metastasis (DM), prostate cancer–specific mortality (PCSM), and overall mortality (OM) endpoints. European Urology Oncology 2018 1, DOI: ( /j.euo ) Copyright © 2018 European Association of Urology Terms and Conditions
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Fig. 4 Estimated cumulative incidence of (A) distant metastases (DM) and (B) prostate cancer–specific mortality (PCSM) following biochemical recurrence (BCR) for patients aged 50 and 70 yr for time to BCR of 1.5, 3, and 5 yr after salvage radiotherapy (SRT). European Urology Oncology 2018 1, DOI: ( /j.euo ) Copyright © 2018 European Association of Urology Terms and Conditions
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