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Published byStephen Sparks Modified over 6 years ago
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Don’t Get Comfortable New semester - new seats A fresh start!
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DNA How many cells are in a human body?
What do you know about chromosomes? What do you know about zygotes/embryos?
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Mitosis and Cell Division
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Chromosomes Single molecules of DNA, containing thousands of genes
Humans have 23 pairs or 46 total Normally you can’t tell them apart- called chromatin
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Chromosome vs. Replicated Chromosome
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Purpose of Mitosis To copy the nucleus so that two new cells may form by cell division
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Importance of Mitosis How we grow from a single cell (zygote) into approximately 100 trillion cells
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Identical DNA Despite very different appearances and functions every cell in your body has the exact same DNA- because they all came from one original cell dividing Differences are due to very complex mechanisms of gene expression that we are only beginning to understand
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Other functions of Mitosis
Grow new cells or repair tissues Only some cells are capable of regenerating (i.e. skin cells constantly divide, brain cells do not)
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Stages of the Cell Cycle
Interphase – cell grows and prepares for division Mitosis – nucleus divides Prophase Metaphase Anaphase Telophase Cytokinesis- Cell divides (overlaps with mitosis)
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Interphase G1- cell grows and copies necessary molecules/organelles
S – chromosomes are copied G2- cell grows and prepares to divide
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Prophase Nucleus starts to disappear Chromosomes Condense
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Metaphase Replicated chromosomes line up
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Anaphase The identical copies of each chromosome are pulled apart and separated
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Telophase 2 new nuclei form, each with the full set of chromosomes
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Cytokinesis The cell splits into 2
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Animate the Process Your quiz will be to demonstrate the process using pipe cleaners- so you need to understand the order of what happens Either make a cartoon, a flipbook, or computer animations showing what happens Doesn’t need to be crazy fancy – but should be accurate and should help you remember how this process goes
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Control of Mitosis The steps are usually closely regulated by “checkpoints” – which prevent the process from continuing if something is wrong
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When Mitosis Is Not Controlled…
It leads to cancer
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Facts about Cancer Over 100 types – just about any part of the body can become cancerous (usually parts of the body that undergo mitosis often!) Around 8-9 million people in the world die each year of cancer (and its increasing!) 30% of cancers could be prevented- mainly by avoiding tobacco and eating a healthy diet (according to the World Health Organization*)
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Cancer in the US 1.5 million new cases and about 570,000 deaths per year 2nd leading cause of death (1in 4) Estimated to cost the country $228 billion per year From Radiation Therapy Answers px
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Cancer Research As a group pick a type of cancer
Conduct some basic research What is the cancer? What might cause it? How prevalent is it? How fatal is it? What are the effects? Can it be cured? What else should we know about the cancer? Should be basic – 2-4 minutes. Don’t overload us with text – just a nice overview. Know what you are going to say- don’t read to us!
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Common Types of Cancer Lung Breast Skin Prostate Leukemia Lymphoma
Pancreatic Thyroid Kidney Colorectal Bladder Endometrial (uterine)
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