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Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial  Andres Acosta, Michael Camilleri,

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Presentation on theme: "Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial  Andres Acosta, Michael Camilleri,"— Presentation transcript:

1 Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial  Andres Acosta, Michael Camilleri, Gururaj Kolar, Johanna Iturrino, Lawrence A. Szarka, Amy Boldingh, Duane Burton, Michael Ryks, Deborah Rhoten, Alan R. Zinsmeister, Sharon C. Spence, Keith Gottesdiener, Ernest P. Bouras, Maria I. Vazquez-Roque  Clinical Gastroenterology and Hepatology  Volume 13, Issue 13, Pages e1 (December 2015) DOI: /j.cgh Copyright © 2015 AGA Institute Terms and Conditions

2 Figure 1 (A) Study design. (B) CONSORT flow chart. GI, gastrointestinal; sc, subcutaneously. Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

3 Figure 2 Bowel movements during baseline and treatment phases. (A) Number of SBMs per week (P < .001), and (B) ease of passage of SBMs (P = .11). Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

4 Figure 3 Time to first BM after first treatment dose. (A) Mean ± SEM and (B) cumulative proportion plot for time to first BM (P = .004). Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions


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