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Volume 4, Issue 1, Pages (January 2018)

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Presentation on theme: "Volume 4, Issue 1, Pages (January 2018)"— Presentation transcript:

1 Volume 4, Issue 1, Pages 30-32 (January 2018)
Clinical and molecular categorization of progressive, adult-onset cutaneous mastocytosis  Courtney Tate, BSc (Hons), MBBS, PhD, Fiona Tang, BMedSc, MBBS, FRCPA, Steven W. Lane, MBBS (Hons), PhD, FRACP, FRCPA, Louise Seymour, MBBS, BPharm (Hons), MPhil, FRCPA  JAAD Case Reports  Volume 4, Issue 1, Pages (January 2018) DOI: /j.jdcr Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A maculopapular telangiectatic rash on the patient's right breast. JAAD Case Reports 2018 4, 30-32DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Skin biopsy at initial presentation of affected area on right breast shows mast cells highlighted by immunoperoxidase stain CD117 (c-kit). JAAD Case Reports 2018 4, 30-32DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Basal serum tryptase increasing over time.
JAAD Case Reports 2018 4, 30-32DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Bone marrow aspirate from patient after symptom progression has clot section with mast cell aggregate admixed with small mature lymphocytes highlighted by immunoperoxidase stain CD117 (c-kit). Some mast cells have atypical spindle-shaped morphology. JAAD Case Reports 2018 4, 30-32DOI: ( /j.jdcr ) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions


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