1. Improved air trapping evaluation in chest computed tomography in children with cystic fibrosis using real-time spirometric monitoring and biofeedback 
Thomas Kongstad, Frederik F. Buchvald, Kent Green, Anders Lindblad, Terry E. Robinson, Kim G. Nielsen 
Journal of Cystic Fibrosis 
Volume 12, Issue 6, Pages (December 2013)
DOI: /j.jcf
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

2. Fig. 1
Computer biofeedback displaying dynamic volume-time curve during scanning. The red lines mark the 10% and 90% of Slow Vital Capacity volumes to be reached for expiratory and inspiratory sequences. Refer to online supplement for a short video of the bio-feedback animation. Volume-time data are stored for documentation and post-processing.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

3. Fig. 2
The child is placed in the scanner with the monitor and the pneumotachograph held in place by a support arm.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

4. Fig. 3
Examples of expiratory images with Point Of Interest-markings of unaffected lung tissue without airtrapping, consolidation or large vessels. The mean value of attenuation inside the circle is registered.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

5. Fig. 4
Lung attenuation during inspiratory and expiratory sequences for the Copenhagen A) and Gothenburg B) group. A successful breath hold manoeuvre provides a large change in attenuation between sequences.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

6. Fig. 5
Air trapping scores in the Copenhagen (CPH) and Gothenburg (GTB) centre. A maximum score of 12 is given if air trapping is seen in more than 50% of lung tissue in all 3 expiratory images. The GTB group scores are significantly lower than the CPH group (p<0.0001).
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

7. Fig. 6
Scatter plot showing the correlation between air trapping score and delta attenuation. (R=0.57 p<0.0001) An ineffective breath hold manoeuvre with a small change in lung attenuation is more likely to result in a low air trapping score.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

8. Supplementary Fig. 1
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

9. Supplementary Fig. 2
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

10. Supplementary Fig. 3
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

11. Supplementary Fig. 4
A plot of HU densities on 1mm vs. 3mm slice thicknesses.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions