1. Outcomes post cardiac surgery in patients treated with fenoldopam vs dopamine
End point
Fenoldopam, n (%)
Dopamine, n (%) p
Acute renal failure (25% increase in serum creatinine from baseline)
17 (42.5)
16 (40)
0.9
Renal replacement therapy
4 (10)
Death
3 (7.5)
0.5
Bove T et al Circulation 2005; 111:

2. Outcomes with fenoldopam vs placebo in patients with acute tubular necrosis
End point
Fenoldopam, n (%)
Placebo,
n (%) p
Dialysis therapy and/or death at 21 days
22 (27.5)
29 (38.7)
0.235
Dialysis therapy
13 (16.25)
19 (25.3)
0.163
Death at 21 days (%)
13.8
25.3
0.068
Tumlin JA et al. Am J Kidney Dis 2005; 46: