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Published byHadi Tan Modified over 5 years ago
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Fig. 6. N95BA5 biocompatibility beyond intended use frame.
N95BA5 biocompatibility beyond intended use frame. (A) Series of histological cross sections prepared for control (left pairs) and treatment (right pairs) in hematoxylin and eosin (H&E) and Masson’s trichrome stain for each of the study endpoints (t = 48 hours, 1 week, and 4 week). Scale bars, 800 μm. (B) Increased magnification of one of the laceration margins for the treatment group showing evolution of the tissue-hydrogel interface from acute inflammatory infiltrate to a mature, compact fibrotic encapsulation layer at 4 weeks. Scale bars, 50 μm. (C) Gross visualization (top row) and high-magnification (bottom row) evaluation of treatment group retinas showing no evidence of trauma-induced retinal detachment or hydrogel-induced retinal neurotoxicity. Scale bars, 5 mm (top row) and 100 μm (bottom row). Niki Bayat et al., Sci Transl Med 2017;9:eaan3879 Published by AAAS
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