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Christine W. Duarte, PhD, Adam W. Black, Kimberly Murray, Amy E

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Presentation on theme: "Christine W. Duarte, PhD, Adam W. Black, Kimberly Murray, Amy E"— Presentation transcript:

1 Validation of the Patient-Reported Outcome Mortality Prediction Tool (PROMPT) 
Christine W. Duarte, PhD, Adam W. Black, Kimberly Murray, Amy E. Haskins, Lee Lucas, Sarah Hallen, Paul K.J. Han, MD, MA, MPH  Journal of Pain and Symptom Management  Volume 50, Issue 2, Pages e6 (August 2015) DOI: /j.jpainsymman Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

2 Fig. 1 ROC curve for the PROMPT in the Maine Medical Center (MMC) validation sample (original and updated are equivalent): AUC (95% CI) = 0.73 (0.63, 0.82). ROC = receiver operating characteristic curve; PROMPT = Patient-Reported Outcome Mortality Prediction Tool. Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

3 Fig. 2 Calibration curves and predicted risk histograms for the original and updated PROMPT models. Calibration curves are plotted for five quantiles of predicted probability in the MMC validation sample (Hosmer-Lemeshow P-value = 0.005 for original PROMPT and 0.66 for the updated PROMPT), and predicted risk histograms are plotted at 10% intervals in predicted risk in the Maine Medical Center (MMC) validation sample. Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

4 Fig. 3 Decision curve for the updated PROMPT with maximum net benefit shown (given by 6.9%, the six-month mortality rate). The dotted line represents net benefit of a “treat all” strategy, whereas the net benefit of a “treat none” strategy is always zero. Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

5 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

6 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

7 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

8 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

9 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

10 Journal of Pain and Symptom Management 2015 50, 241-247. e6DOI: (10
Journal of Pain and Symptom Management  , e6DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

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