Presentation is loading. Please wait.

Presentation is loading. Please wait.

The incidence of heparin-induced antibodies in patients undergoing vascular surgery: A prospective study  Mark R. Jackson, MD, David L. Gillespie, MD,

Published byAntoinette Roux Modified over 5 years ago

Similar presentations

Presentation on theme: "The incidence of heparin-induced antibodies in patients undergoing vascular surgery: A prospective study  Mark R. Jackson, MD, David L. Gillespie, MD,"— Presentation transcript:

1 The incidence of heparin-induced antibodies in patients undergoing vascular surgery: A prospective study  Mark R. Jackson, MD, David L. Gillespie, MD, Audrey S. Chang, PhD, Elizabeth G. Longenecker, BS, RN, Raquel A. Peat, Barbara M. Alving, MD  Journal of Vascular Surgery  Volume 28, Issue 3, Pages (September 1998) DOI: /S (98) Copyright © 1998 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Schematic illustration of heparin/PF4 ELISA. Heparin-induced IgG antibodies from patient plasma bind the complex of heparin and PF4 in ELISA microtiter plate. Heparin-induced IgG antibodies (if present) are detected after incubation with alkaline phosphatase-labeled goat anti-human IgG and color development with enzyme substrate. Journal of Vascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Box plots of quantitative ELISA results before and after vascular surgery. Groups are separately analyzed based on prior heparin exposure. Box plots depict the 25th to 75th percentiles for ODR values within the box. The horizontal line within the box is the median value. Extreme values are depicted by arrow bars. Journal of Vascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Scatter plot of change in ODR (postoperative ODR minus baseline ODR) as a function of intraoperative heparin dose. The middle line is the linear regression line for mean values. Upper and lower lines represent the range of the 95% confidence interval. Journal of Vascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Download ppt "The incidence of heparin-induced antibodies in patients undergoing vascular surgery: A prospective study  Mark R. Jackson, MD, David L. Gillespie, MD,"

Similar presentations

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,
The role of arteriovenous shunts in the pathogenesis of varicose veins Howard C. Baron, M.D., Sebastiano Cassaro, M.D. Journal of Vascular Surgery Volume.

The role of arteriovenous shunts in the pathogenesis of varicose veins Howard C. Baron, M.D., Sebastiano Cassaro, M.D. Journal of Vascular Surgery Volume.
The effect of inguinal lymphatic manipulation on regional lymph flow patterns Jeffrey R. Rubin, MD, Lisa B. Eberlin, MD Journal of Vascular Surgery Volume.

The effect of inguinal lymphatic manipulation on regional lymph flow patterns Jeffrey R. Rubin, MD, Lisa B. Eberlin, MD Journal of Vascular Surgery Volume.
S. Sulaiman Shoab, MD, FCPS, FRCS, J. H. Scurr, MS, FRCS, P. D

S. Sulaiman Shoab, MD, FCPS, FRCS, J. H. Scurr, MS, FRCS, P. D
A review of 100 consecutive reconstructions of the distal vertebral artery for embolic and hemodynamic disease  Ramon Berguer, MD, PhD, Mark D. Morasch,

A review of 100 consecutive reconstructions of the distal vertebral artery for embolic and hemodynamic disease  Ramon Berguer, MD, PhD, Mark D. Morasch,
Clinical evaluation of recombinant human platelet – derived growth factor for the treatment of lower extremity diabetic ulcers  David L. Steed, MD, the.

Clinical evaluation of recombinant human platelet – derived growth factor for the treatment of lower extremity diabetic ulcers  David L. Steed, MD, the.
Heparin-coated catheters and heparin-induced thrombocytopenia

Heparin-coated catheters and heparin-induced thrombocytopenia
Do patients with the heparin-induced thrombocytopenia syndrome have heparin-specific antibodies?  John G. Adams, MD, Loren J. Humphrey, MD, PhD, Xinchao.

Do patients with the heparin-induced thrombocytopenia syndrome have heparin-specific antibodies?  John G. Adams, MD, Loren J. Humphrey, MD, PhD, Xinchao.
The progressive nature of peripheral arterial disease in young adults: A prospective analysis of white men referred to a vascular surgery service  R.James.

The progressive nature of peripheral arterial disease in young adults: A prospective analysis of white men referred to a vascular surgery service  R.James.
Axillary-to-carotid artery bypass grafting for symptomatic severe common carotid artery occlusive disease  Joseph P. Archie, PhD, MD  Journal of Vascular.

Axillary-to-carotid artery bypass grafting for symptomatic severe common carotid artery occlusive disease  Joseph P. Archie, PhD, MD  Journal of Vascular.
Foot volumetry can predict recurrent ulceration after subfascial ligation of perforators and saphenous ligation  A.W. Bradbury, BSc, MD, FRCSEd, C.V.

Foot volumetry can predict recurrent ulceration after subfascial ligation of perforators and saphenous ligation  A.W. Bradbury, BSc, MD, FRCSEd, C.V.
Fetal internal iliac artery: Case report and embryologic review

Fetal internal iliac artery: Case report and embryologic review
Impact of a critical pathway on postoperative length of stay and outcomes after infrainguinal bypass  Andrew C. Stanley, MD, Maryann Barry, RN, Thayer.

Impact of a critical pathway on postoperative length of stay and outcomes after infrainguinal bypass  Andrew C. Stanley, MD, Maryann Barry, RN, Thayer.
Scott D. Gitlin, MD, Michael Deeb, MD, Christopher Yann, BS, Alvin H

Scott D. Gitlin, MD, Michael Deeb, MD, Christopher Yann, BS, Alvin H
A new valvulotome for in situ bypass grafts

A new valvulotome for in situ bypass grafts
Computed electroencephalographic topographic brain mapping

Computed electroencephalographic topographic brain mapping
Hemostatic efficacy of a fibrin sealant–based topical agent in a femoral artery injury model: A randomized, blinded, placebo-controlled study  Mark R.

Hemostatic efficacy of a fibrin sealant–based topical agent in a femoral artery injury model: A randomized, blinded, placebo-controlled study  Mark R.
Relationship of severity of lower limb peripheral vascular disease to mortality and morbidity: A six-year follow-up study  Mary A. Howell, MD, Mary Paula.

Relationship of severity of lower limb peripheral vascular disease to mortality and morbidity: A six-year follow-up study  Mary A. Howell, MD, Mary Paula.
Malcolm O. Perry, MD, Richard Kempczinski, MD 

Malcolm O. Perry, MD, Richard Kempczinski, MD 
Protecting the brain and spinal cord

Protecting the brain and spinal cord

Similar presentations

Ads by Google