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Some ideas for the project

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Presentation on theme: "Some ideas for the project"— Presentation transcript:

1 Some ideas for the project
DNA globule formation with attractive nanoparticles – chromatin conformation Entropy as the driver of chromosome segregation Suckjoon Jun1 & Andrew Wright2 Nature Microbiology, 2010

2 Micelle formation by amphiphilic molecules with coarse-grained Lennard-Jones potentials.

3 r Two particles in a polymer solution : Applicable for
Measuring the entropically-induced potentials between two colloids. Two particles in a polymer solution : depletion layer exclusion zone Polymer approximated as “phantom spheres” Applicable for Rg/R << 1 cp/cp* << 1 Ideal Solvent 2Rg Asakura & Oosawa, J Polymer Science Vol 33, p. 183 (1958) Verma, Crocker, Yodh, Phys Rev Lett, , 1998. Entropy-driven interparticle attraction Approximations not valid for non-dilute mixtures or Rg ~ R D D+2Rg r

4 Stability of colloids with DLVO interactions
𝐸 𝑖𝑗 = 𝑖,𝑗 𝑞 𝑖 𝑞 𝑗 𝑟 𝑖𝑗 𝑒 −𝜅𝑟 + 𝜖 𝜎 𝑟 𝑖𝑗 − 𝜎 𝑟 𝑖𝑗 6 Model the stability of colloidal suspension with Lennard-Jones interactions and electrostatic interactions. With fixed Lennard-Jones parameters (A,B), how does the suspension stability depend on the electrostatic screening length (Debyle length) k-1?


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