1. Optimizing Accuracy of Laboratory Testing: Team-Based Strategies to Reduce Biotin Concerns

3. Physicians Rely on Accurate Laboratory Results

4. Emerging Problem of Biotin Interference in Immunoassays

5. Dietary Sources

6. Laboratory Errors Can Occur in the 3 Phases of the Testing Process

7. Sources of Analytical Error in Clinical Immunoassays

8. Biotin: Interference in Immunoassays

9. Non-Competitive Immunoassays

10. Competitive Immunoassays

11. Noncompetitive vs Competitive Immunoassay

12. Interference Example

13. UCDMC Endocrinology Population

14. UC Davis Thyroid Testing Population

15. Biotin in TSH and Troponin Testing

16. Biotin in TSH and Troponin Testing (cont)

17. Affected Laboratory Testing

18. High-Sensitivity Cardiac Troponin Assay

19. UC Davis Summary

20. Key Point: Biotin Interference Is Preventable

21. Health History: Avoid Issues Later

22. Ask When Was Biotin Taken

23. Educate All Disciplines on Many Platforms

24. Multidisciplinary Team System Approaches

25. Key Takeaways: Clinicians' Responsibilities

26. Attention Emergency Medicine Clinicians

27. Rare But Be Aware

28. Abbreviations