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Ichthyosis cribriformis: A new entity?

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Presentation on theme: "Ichthyosis cribriformis: A new entity?"— Presentation transcript:

1 Ichthyosis cribriformis: A new entity?
Hiram Larangeira de Almeida, MD, Rudolf Happle, MD, Ulrike Blume-Peytavi, MD, Luis Antônio Suita de Castro, MSc  Journal of the American Academy of Dermatology  Volume 58, Issue 3, Pages (March 2008) DOI: /j.jaad Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Back aspect of left hand.
Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Thickening of skin over ankles with detail of skin surface (inset). Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 A, Keratotic plugs on back of hand. B, On extensor surface of knee, keratotic plugs and depressions. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Light microscopy showing papillomatosis, orthohyperkeratosis, and focal hypergranulosis. (Hematoxylin-eosin stain; original magnification: ×400.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

6 Fig 5 Light microscopy demonstrating keratotic conus. (Hematoxylin-eosin stain; original magnification: ×100.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

7 Fig 6 Transmission electron microscopy showing keratin filaments (K) and mitochondria with irregular shape and sizes (arrows). (Original magnification × ) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

8 Fig 7 Therapeutic effect of oral isotretinoin on wrist (A) and ankle (B). After elimination of hyperkeratosis sievelike aspect became more evident (insets). Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions


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