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Mary H. Nieuwenhuis, Lisbeth M. Mathus–Vliegen, Frederik J

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Presentation on theme: "Mary H. Nieuwenhuis, Lisbeth M. Mathus–Vliegen, Frederik J"— Presentation transcript:

1 Genotype-Phenotype Correlations as a Guide in the Management of Familial Adenomatous Polyposis 
Mary H. Nieuwenhuis, Lisbeth M. Mathus–Vliegen, Frederik J. Slors, Gerrit Griffioen, Fokko M. Nagengast, Wim R. Schouten, Jan H. Kleibeuker, Hans F.A. Vasen  Clinical Gastroenterology and Hepatology  Volume 5, Issue 3, Pages (March 2007) DOI: /j.cgh Copyright © 2007 AGA Institute Terms and Conditions

2 Figure 1 Distribution of APC mutations in 138 Dutch FAP families.
Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions

3 Figure 2 Cumulative risk of rectal excision until 20 years after IRA, per mutation group. Log rank P = Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions

4 Figure 3 Cumulative risk of rectal cancer until 15 years after IRA, per mutation group. Log rank P = Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions


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