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KRAS Mutation Analysis Helps to Differentiate Between Pulmonary Metastasis from Colon Adenocarcinoma In Situ and Primary Lung Adenocarcinoma  Taylor M.

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Presentation on theme: "KRAS Mutation Analysis Helps to Differentiate Between Pulmonary Metastasis from Colon Adenocarcinoma In Situ and Primary Lung Adenocarcinoma  Taylor M."— Presentation transcript:

1 KRAS Mutation Analysis Helps to Differentiate Between Pulmonary Metastasis from Colon Adenocarcinoma In Situ and Primary Lung Adenocarcinoma  Taylor M. Ortiz, MD, David W. Cohen, MD, Michael S. Kent, MD, Pasi A. Jänne, MD, PhD, Daniel B. Costa, MD, PhD  Journal of Thoracic Oncology  Volume 6, Issue 1, Pages (January 2011) DOI: /JTO.0b013e3181f8a164 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 A, Computed tomography of the lung. B, Positron emission tomography. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e3181f8a164) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 A, Lung with left upper lobe adenocarcinoma (hematoxylin and eosin). B, Sigmoid polyp with high-grade dysplasia (hematoxylin and eosin). Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e3181f8a164) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Immunohistochemical profile of the resected tumor. A, CK7; (B) CK20; (C) TTF-1; (D) CDX-2. CK, cytokeratin; TTF-1, thyroid transcription factor-1; CDX-2, caudal type homeobox transcription factor 2. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e3181f8a164) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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