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Reversal of Overanticoagulation in Very Elderly Hospitalized Patients with an INR above 5.0: 24-Hour INR Response after Vitamin K Administration Eric Pautas, MD, PhD, Isabelle Peyron, PharmD, Samir Bouhadiba, PharmD, Jean-Louis Golmard, MD, PhD, Adeline Gouronnec, MD, Nadine Oboa, PharmD, Virginie Siguret, PhD, Isabelle Gouin-Thibault, PhD The American Journal of Medicine Volume 124, Issue 6, Pages (June 2011) DOI: /j.amjmed Copyright © 2011 Elsevier Inc. Terms and Conditions
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Figure 1 Distribution of concomitant medications (number/patient).
The American Journal of Medicine , DOI: ( /j.amjmed ) Copyright © 2011 Elsevier Inc. Terms and Conditions
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Figure 2 Day 0 and Day 1 international normalized ratios (INRs), and P values for the difference: (A) 217 Day 0 INRs managed according to recommendations. (B) 121 Day 0 INRs between 5.0 and 6.0 managed with VKA dose omission and vitamin K1 administration according to recommendations. (C) 48 Day 0 INRs between 5.0 and 6.0 managed with VKA dose omission but no vitamin K1 administration. The therapeutic range is represented by the rectangle. The American Journal of Medicine , DOI: ( /j.amjmed ) Copyright © 2011 Elsevier Inc. Terms and Conditions
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