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Low-Dose International Normalized Ratio Self-Management: A Promising Tool to Achieve Low Complication Rates After Mechanical Heart Valve Replacement 

Published bySherman Gregory Barker Modified over 6 years ago

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Presentation on theme: "Low-Dose International Normalized Ratio Self-Management: A Promising Tool to Achieve Low Complication Rates After Mechanical Heart Valve Replacement "— Presentation transcript:

1 Low-Dose International Normalized Ratio Self-Management: A Promising Tool to Achieve Low Complication Rates After Mechanical Heart Valve Replacement  Heinrich Koertke, MD, Armin Zittermann, PhD, Kazutomo Minami, MD, Gero Tenderich, MD, Otto Wagner, Mahmoud El-Arousy, MD, Arno Krian, MD, Juergen Ennker, MD, Uwe Taborski, MD, Wolf Peter Klövekorn, MD, Rainer Moosdorf, MD, Werner Saggau, MD, Michiel Morshuis, MD, Jan Koerfer, MD, Dirk Seifert, MD, Reiner Koerfer, MD  The Annals of Thoracic Surgery  Volume 79, Issue 6, Pages (June 2005) DOI: /j.athoracsur Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 International normalized ratio (INR) values of patients with INR self-management: (A) Low dose of anticoagulation and aortic valve replacement. (B) Conventional dose of anticoagulation and aortic valve replacement. (C) Low dose of anticoagulation and mitral or double valve replacement. (D) Conventional dose of anticoagulation and mitral or double valve replacement. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 International normalized ratio (INR) values within the therapeutic range in patients with low-dose (solid squares) or conventional-dose (solid circles) INR self-management over time (reha = rehabilitation.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 International normalized ratio (INR) values in patients with INR self-management according to schooling. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 International normalized ratio (INR) values in patients with INR self-management in relation to age. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Freedom from grade III complications (heart valve prosthesis thrombosis or severe thromboembolism that required inpatient treatment or caused long-term impairment, including transient ischemic attacks) in patients with low-dose or conventional-dose international normalized ratio self-management. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Survival of patients with international normalized ratio self-management and low-dose or conventional dose of anticoagulation therapy. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

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