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Volume 150, Issue 3, Pages 581-590.e4 (March 2016)
Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis Ekaterina Safroneeva, Alex Straumann, Michael Coslovsky, Marcel Zwahlen, Claudia E. Kuehni, Radoslaw Panczak, Nadine A. Haas, Jeffrey A. Alexander, Evan S. Dellon, Nirmala Gonsalves, Ikuo Hirano, John Leung, Christian Bussmann, Margaret H. Collins, Robert O. Newbury, Giovanni De Petris, Thomas C. Smyrk, John T. Woosley, Pu Yan, Guang-Yu Yang, Yvonne Romero, David A. Katzka, Glenn T. Furuta, Sandeep K. Gupta, Seema S. Aceves, Mirna Chehade, Jonathan M. Spergel, Alain M. Schoepfer Sami R. Achem, Amindra S. Arora, Oral Alpan, David Armstrong, Stephen E. Attwood, Joseph H. Butterfield, Michael D. Crowell, Kenneth R. DeVault, Eric Drouin, Benjamin Enav, Felicity T. Enders, David E. Fleischer, Amy Foxx-Orenstein, Dawn L. Francis, Gordon H. Guyatt, Lucinda A. Harris, Amir F. Kagalwalla, Hirohito Kita, Murli Krishna, James J. Lee, John C. Lewis, Kaiser Lim, G. Richard Locke, Joseph A. Murray, Cuong C. Nguyen, Diana M. Orbelo, Shabana F. Pasha, Francisco C. Ramirez, Javed Sheikh, Sarah B. Umar, Catherine R. Weiler, John M. Wo, Tsung-Teh Wu, Kathleen J. Yost Ekaterina Safroneeva, Alex Straumann, Michael Coslovsky, Marcel Zwahlen, Claudia E. Kuehni, Radoslaw Panczak, Nadine A. Haas, Jeffrey A. Alexander, Evan S. Dellon, Nirmala Gonsalves, Ikuo Hirano, John Leung, Christian Bussmann, Margaret H. Collins, Robert O. Newbury, Giovanni De Petris, Thomas C. Smyrk, John T. Woosley, Pu Yan, Guang-Yu Yang, Yvonne Romero, David A. Katzka, Glenn T. Furuta, Sandeep K. Gupta, Seema S. Aceves, Mirna Chehade, Jonathan M. Spergel, Alain M. Schoepfer Sami R. Achem, Amindra S. Arora, Oral Alpan, David Armstrong, Stephen E. Attwood, Joseph H. Butterfield, Michael D. Crowell, Kenneth R. DeVault, Eric Drouin, Benjamin Enav, Felicity T. Enders, David E. Fleischer, Amy Foxx-Orenstein, Dawn L. Francis, Gordon H. Guyatt, Lucinda A. Harris, Amir F. Kagalwalla, Hirohito Kita, Murli Krishna, James J. Lee, John C. Lewis, Kaiser Lim, G. Richard Locke, Joseph A. Murray, Cuong C. Nguyen, Diana M. Orbelo, Shabana F. Pasha, Francisco C. Ramirez, Javed Sheikh, Sarah B. Umar, Catherine R. Weiler, John M. Wo, Tsung-Teh Wu, Kathleen J. Yost Gastroenterology Volume 150, Issue 3, Pages e4 (March 2016) DOI: /j.gastro Copyright © 2016 AGA Institute Terms and Conditions
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Figure 1 Receiver operator curve analysis was carried out to determine the best EEsAI PRO score cutoff value to detect endoscopic inflammatory remission (A), endoscopic fibrotic remission (B), endoscopic inflammatory and fibrotic remission (C), histologic remission defined as peak eosinophil count of <20/mm2 (D), histologic remission defined as peak eosinophil count of <60/mm2 (E), and deep remission defined as the combination of endoscopic inflammatory and fibrotic remission as well as histologic remission (peak eosinophil count of <20/mm2) (F). eos, eosinophils; OPT, optimal. Gastroenterology , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions
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Supplementary Figure 1 Receiver operator curve analysis was carried out to determine the best EEsAI PRO score cutoff value to detect endoscopic fibrotic remission (A) and deep remission (B) in EoE patients that underwent esophageal dilation in the last 12 months before inclusion. The EEsAI PRO score of 25 points had an overall accuracy of 77.4% to detect patients in endoscopic fibrotic remission. The EEsAI PRO score of 25 points had an overall accuracy of 71.7% to detect patients in deep remission. Deep remission defined as combined endoscopic fibrotic and inflammatory remission as well as histologic remission (cutoff value of <20 eosinophils/mm2). OPT, optimal. Gastroenterology , e4DOI: ( /j.gastro ) Copyright © 2016 AGA Institute Terms and Conditions
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