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Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies  Dr.

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Presentation on theme: "Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies  Dr."— Presentation transcript:

1 Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies  Dr Grant A Mackenzie, PhD, Prof Philip C Hill, MD, Shah M Sahito, MPH, David J Jeffries, PhD, Ilias Hossain, MPH, Christian Bottomley, PhD, Uchendu Uchendu, MD, David Ameh, MPH, Malick Ndiaye, DP, Chidebereh D Osuorah, MPH, Oyedeji Adeyemi, MBBS, Jayani Pathirana, MSc, Yekini Olatunji, MBChB, Bade Abatan, MBChB, Ebirim Ahameefula, MBBS, Bilquees S Muhammad, MBBS, Augustin E Fombah, MD, Debasish Saha, PhD, Roslyn Mackenzie, FRACGP, Ian Plumb, MBBS, Aliu Akano, FMCR, Bernard Ebruke, FWACP, Readon C Ideh, FWACP, Bankole Kuti, FWACP, Peter Githua, MSc, Emmanuel Olutunde, MBChB, Ogochukwu Ofordile, MBBS, Edward Green, FRCP, Effua Usuf, PhD, Henry Badji, MSc, Usman N A Ikumapayi, MSc, Ahmad Manjang, MSc, Rasheed Salaudeen, BSc, E David Nsekpong, BSc, Sheikh Jarju, DVM, Prof Martin Antonio, PhD, Sana Sambou, MSc, Lamin Ceesay, MSc, Yamundow Lowe- Jallow, MSc, Dawda Sowe, MSc, Momodou Jasseh, PhD, Prof Kim Mulholland, MD, Maria Knoll, PhD, Prof Orin S Levine, PhD, Stephen R Howie, PhD, Prof Richard A Adegbola, PhD, Prof Brian M Greenwood, MD, Prof Tumani Corrah, PhD  The Lancet Infectious Diseases  Volume 17, Issue 9, Pages (September 2017) DOI: /S (17) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

2 Figure 1 Study profile The profile covers the longitudinal observation period in the BHDSS from May 12, 2008, to Dec 31, cases had radiological pneumonia with consolidation, 17 136 had clinical pneumonia, 265 had pneumococcal pneumonia, and 672 had hypoxic pneumonia. All values are crude. The adjustment corrects for trends in the rate of patients presenting who met referral criteria. BHDSS=Basse Health and Demographic Surveillance System. The Lancet Infectious Diseases  , DOI: ( /S (17) ) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

3 Figure 2 Adjusted annual pneumonia incidence
Incidence of radiological pneumonia with consolidation (A), clinical pneumonia (B), pneumococcal pneumonia (C), and hypoxic pneumonia (D) in the Basse Health and Demographic Surveillance System from 2008 to 2015, by age group. Bars show 95% CI. PCV=pneumococcal conjugate vaccine. The Lancet Infectious Diseases  , DOI: ( /S (17) ) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions

4 Figure 3 Case-control study profile
The case-control study investigated the effectiveness of PCV13 against radiological pneumonia with consolidation. PCV=pneumococcal conjugate vaccine. The Lancet Infectious Diseases  , DOI: ( /S (17) ) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Terms and Conditions


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