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X-APL: An Improved Family-Based Test of Association in the Presence of Linkage for the X Chromosome
Ren-Hua Chung, Richard W. Morris, Li Zhang, Yi-Ju Li, Eden R. Martin The American Journal of Human Genetics Volume 80, Issue 1, Pages (January 2007) DOI: /510630 Copyright © 2007 The American Society of Human Genetics Terms and Conditions
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Figure 1 Power comparison for single-marker analysis. Power estimates for the single-marker X-APL, XS-TDT, XPDT, and XMCPDT were based on 2,000 simulated data sets. All families were simulated without parental data except AAU** families, which have both parents present, and AAU* families, which have one parental genotype missing. Power is calculated for both significance levels (α) of .05 and .005 for both the recessive and multiplicative models. The American Journal of Human Genetics , 59-68DOI: ( /510630) Copyright © 2007 The American Society of Human Genetics Terms and Conditions
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