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Volume 137, Issue 3, Pages 865-872 (September 2009)
Prediction of Non-Alcoholic Fatty Liver Disease and Liver Fat Using Metabolic and Genetic Factors Anna Kotronen, Markku Peltonen, Antti Hakkarainen, Ksenia Sevastianova, Robert Bergholm, Lina M. Johansson, Nina Lundbom, Aila Rissanen, Martin Ridderstråle, Leif Groop, Marju Orho–Melander, Hannele Yki–Järvinen Gastroenterology Volume 137, Issue 3, Pages (September 2009) DOI: /j.gastro Copyright © 2009 AGA Institute Terms and Conditions
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Figure 1 The relationship between liver fat content measured using proton magnetic resonance spectroscopy (1H-MRS) and liver fat content predicted from the liver fat equation. Shaded circles denote the estimation group, and open circles denote the validation group. Correlation coefficient and its significance for all subjects is given. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2009 AGA Institute Terms and Conditions
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Figure 2 ROC curves of NAFLD liver fat score in the estimation (solid line) and validation (dashed line) groups. AROC of the estimation group is 0.87 and that of the validation group is The optimal cut-off point (−0.640) with sensitivity of 86% and specificity of 71% determined using the Youden index is shown. In addition, the low cut-off point (−1.413) to predict the presence of increased liver fat with accuracy of 95% and the high cut-off point (1.257) to predict the absence of increased liver fat content with an accuracy of 95% are shown. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2009 AGA Institute Terms and Conditions
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