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Published byRaymond Gregory Modified over 6 years ago
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PROTEINS Polymers (long chains) of AMINO ACIDS
arranged in specific sequence linked by PEPTIDE BONDS range in length from a few to 1000+
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AMINO ACIDS building blocks of proteins
there are 20 common amino acids structure of an amino acid: elements included in a protein: -carbon -hydrogen -oxygen -nitrogen -sulfur (usually)
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Amino acids are linked together through DEHYDRATION SYNTHESIS to form PEPTIDE BONDS
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PROTEIN STRUCTURE a protein’s function depends on its specific 3-D shape
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Protein Shape: determined by environmental conditions
DENATURATION: protein loses its natural shape, and therefore loses its function! This can be caused by: extreme heat pH changes
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HEAT
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Functions of Proteins structural support (e.g. hair, nails)
signaling (e.g. hormones)
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Functions of Proteins • movement (contraction of muscles)
transporting oxygen in the blood
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Functions of Proteins • defense (antibodies of immune system)
catalysis of reactions (ENZYMES)
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PROTEINS WORKING AS ENZYMES
are proteins control the speed of reactions (often they increase the speed of reactions)
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• are not changed or “used up” by a reaction; can be used over and over
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each enzyme is specific to a SUBSTRATE
SUBSTRATE = the substance the enzyme acts on Substrate ==> enzyme-sub.==> product complex enzyme enzyme
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ACTIVE SITE = region of an enzyme which binds to the substrate
is usually a pocket or groove on surface compatible “fit” between shape of enzyme’s active site and shape of substrate
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Factors Affecting Enzyme Activity
Temperature: as temp increases, reaction rate increases BUT, if temp gets too high, enzyme denatures and loses its shape and function optimal range for human enzymes: 35-40°C
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pH: -optimal range for most enzymes: pH 6-8
*some enzymes operate best at extremes of pH (e.g. digestive enzyme pepsin, found in the acidic environment of the stomach, works best at pH 2)
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Nucleic Acids nucleic acids store and transmit hereditary information
Two types of nucleic acids: DNA RNA
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Structure of Nucleic Acids
polymers made up of monomers called NUCLEOTIDES Elements present: -carbon -hydrogen -oxygen -nitrogen -phosphorus
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each nucleotide consists
of: 1. a simple sugar -deoxyribose in DNA -ribose in RNA 2. phosphate group 3. a base (e.g. in DNA, the bases are A, G, C, and T)
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nucleotides are joined together in DEHYDRATION SYNTHESIS
results in a “backbone” with a repeating pattern of sugar-phosphate-sugar-phosphate...
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1. DNA = Deoxyribonucleic acid
forms the genetic code - the instructions for the proteins (amino acid sequences) of an organisms’ proteins is copied and passed from one generation of cells to another
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2. RNA = Ribonucleic acid functions in the actual
synthesis of proteins coded for by DNA
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