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Figure S1. Proteolytic release of MMAE from ASG-5ME

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Presentation on theme: "Figure S1. Proteolytic release of MMAE from ASG-5ME"— Presentation transcript:

1 Figure S1. Proteolytic release of MMAE from ASG-5ME

2 Figure S2. SLC44A4 RNA expression in normal and tumor specimens from combined Oncomine data sets. Linear expression values from a composite of 192 publically available datasets are presented as a scatter plot. Median signal values and the number of outliers are presented based on box plot analysis in Spotfire.

3 Count Count Count FL 2 Log : PE FL 2 Log : PE FL 2 Log : PE Figure S3: Expression of SLC44A4 in OVCAR-5 cells determined by FACS. Blue = anti-SLC44A4 antibody, red = isotype control antibody. A) Low SLC44A4 expression in OVCAR-5 cells cultured in vitro. B) Increased SLC44A4 expression in OVCAR-5 cell line xenografts grown in vivo, digested and grown in vitro for 6 hours. C) Expression decreases to low levels after passaging in vitro.

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