1. T-cell regulation in chronic paranasal sinus disease
Nicholas Van Bruaene, MD, Claudina Angela Pérez-Novo, PhD, Tomasz M. Basinski, MSc, Thibaut Van Zele, MD, Gabriele Holtappels, Natalie De Ruyck, MSc, Carsten Schmidt-Weber, PhD, Cezmi Akdis, MD, Paul Van Cauwenberge, MD, PhD, Claus Bachert, MD, PhD, Philippe Gevaert, MD, PhD 
Journal of Allergy and Clinical Immunology 
Volume 121, Issue 6, Pages e3 (June 2008)
DOI: /j.jaci
Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Expression of FOXP3+ cells in nasal mucosa from healthy individuals (controls, CON) and subjects with CRSsNP or CRSwNP. Lack of staining is observed by blocking with FOXP3-immunizing peptide. Human tonsil sections served as a positive control with FOXP3+ cells located in the parafollicular cortex (T-cell zone). Original magnification was ×200 or ×400. For human tonsil magnification was ×100 or ×400. Representative slides are shown (n = 6 per group).
Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci )
Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
mRNA expression of transcription factors (FOXP3, T-bet, GATA-3) involved in naive T-cell differentiation in controls (CON), CRSwNP, and CRSsNP expressed as logarithm of normalized relative expression units/30 ng cDNA.
Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci )
Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
mRNA expression of key cytokines IFN-γ (TH1), IL-4, IL-5, IL-13 (TH2) (A), and iTreg-related TGF-β1 and IL-10 in controls (CON), CRSsNP, and CRSwNP (B), expressed as logarithm of normalized relative expression units/30 ng cDNA. For TGF-β1 and IFN-γ, additional protein measurements were performed, expressed as picograms per milliliter.
Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci )
Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions