1. Efficacy of transdermal nitroglycerin combined with etodolac for the treatment of chronic post-thoracotomy pain: An open-label prospective clinical trial 
Lucio Glantz, MD, Galina Godovic, MD, Margarita Lekar, MD, Mordechai Kramer, MD, Leonid A Eidelman, MD 
Journal of Pain and Symptom Management 
Volume 27, Issue 3, Pages (March 2004)
DOI: /j.jpainsymman

2. Fig. 1
Intensity of pain in patients with chronic post-thoracotomy pain treated with etodolac alone (Etodolac) and with NTG patch and etodolac (NTG). No clinical improvement was evident after 2 weeks of treatment with etodolac alone (400 mg every 8 hr). After 2 weeks of adjunctive treatment with NTG patch (5 mg per day), significant improvement was observed, from basal VAS 66.7±11 to VAS 42.1±5. ∗P<0.05.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )

3. Fig. 2
Intensity of breakthrough pain in patients with chronic post-thoracotomy pain treated with etodolac alone (Etodolac) and with NTG patch and etodolac. No clinical improvement occurred after 2 weeks of treatment with etodolac alone (400 mg every 8 hr). After 2 weeks of adjunctive treatment with NTG patch (5 mg per day), the intensity of breakthrough attacks significantly decreased from severe pain (VAS 84.7±8) to moderate pain (VAS 60.5±3). ∗P<0.05.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )

4. Fig. 3
Effect of etodolac alone (Etodolac) and NTG/etodolac (NTG) on sleep efficiency (% sleep hr /time in bed). No clinical improvement occurred after 2 weeks of treatment with etodolac alone. After 2 weeks of adjunctive treatment with NTG patch, sleep efficiency improved from a mean of 58.2±12% to 82.6±4%. ∗P<0.05.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )