1. Volume 126, Issue 4, Pages 1115-1121 (April 2004)
An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells 
Andrea J. Gerth, Ling Lin, Markus F. Neurath, Laurie H. Glimcher, Stanford L. Peng 
Gastroenterology 
Volume 126, Issue 4, Pages (April 2004)
DOI: /j.gastro

2. Figure 1
IBD in the absence of NFATc2 and lymphocytes. (Upper panels) Animals of the genotypes indicated were observed at the ages indicated for weight and the presence of rectal prolapse. The percentages of animals without prolapse were plotted against age. (Lower panels) Colitis scores were determined in representative animals of the genotypes indicated. DO11: anti-OVA (DO11.10) TCR transgenic; HEL Ig, anti-HEL (MD4HEL) Ig transgenic.
Gastroenterology  , DOI: ( /j.gastro )

3. Figure 2
IBD pathology in the absence of NFATc2 and lymphocytes. (A ) Rectal prolapse in a 16-week-old NFATc2-deficient RAG-deficient mouse, representative of all genotypes that developed rectal prolapse (Figure 1): NFATc2−/− RAG−/−, NFATc2−/− RAG−/− DO.11+, and NFATc2−/− RAG−/− HEL Ig+. (B and C ) Histology from the prolapsed rectum of a 16-week-old NFATc2-deficient RAG-deficient mouse (B, 4×; C, 20×). Arrow indicates a crypt abscess. Immunohistological staining shows both CD18-reactive (D, 10×) and Ly-6G-reactive (E, 10×) cells. adv, adventitia; lp, lamina propria.
Gastroenterology  , DOI: ( /j.gastro )

4. Figure 3
Role of B lymphocytes in the suppression of IBD. Whole splenocytes, T cells, or B cells from wild-type (WT) or NFATc2-deficient (RAG+/+; KO) animals were adoptively transferred to 6-week-old NFATc2−/− RAG−/− animals. Where indicated, animals were simultaneously treated with rat immunoglobulin G control or a combination of neutralizing anti-IL-10 and anti-IL-10 receptor antibodies. Weights were assessed at the ages indicated; n = 10 in each group. Colitis scores were determined in representative animals of the transfer populations indicated. T or B cell populations, or both (as appropriate to the donor population), in the lymphoid organs of adoptively transferred recipients were comparable to those of wild-type animals, confirming reconstitution (not shown).
Gastroenterology  , DOI: ( /j.gastro )