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The Declaration of Independence of the Neurovascular Intimacy

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1 The Declaration of Independence of the Neurovascular Intimacy
Sophie Chauvet, Fanny Mann  Neuron  Volume 80, Issue 2, Pages (October 2013) DOI: /j.neuron Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Two Models of Neurovascular Congruency
(Left) “One-patterns-the-other” model in which either the nervous or vascular system instructs the other system to form using its established architecture as a template. This model allows for the parallel trajectories of nerves and vessels, independent of their position relative to their surroundings. (Right) “Independent-patterning” model in which balanced attractive and repulsive signals originating from the central organizer—the target tissue—pattern neurovascular congruency. When nerves and vessels reach their target tissues, the precise architecture of the trio of nerves, vessels, and target tissues becomes functionally relevant according to the unique requirement of the target tissue. Neuron  , DOI: ( /j.neuron ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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