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Analysis of Availability and Access of Anti-myeloma Drugs and Impact on the Management of Multiple Myeloma in Latin American Countries  Roberto José Pessoa.

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Presentation on theme: "Analysis of Availability and Access of Anti-myeloma Drugs and Impact on the Management of Multiple Myeloma in Latin American Countries  Roberto José Pessoa."— Presentation transcript:

1 Analysis of Availability and Access of Anti-myeloma Drugs and Impact on the Management of Multiple Myeloma in Latin American Countries  Roberto José Pessoa de Magalhães Filho, Edvan Crusoe, Eloisa Riva, Willen Bujan, Guilhermo Conte, Juan Ramon Navarro Cabrera, Diana Katerine Garcia, Guilhermo Quintero Vega, Jose Macias, Jose Willian Oliveros Alvear, Mercedes Royg, Lidiane Andino Neves, Jose Luis Lopez Dopico, German Espino, Douglas Rosales Ortiz, Zurelis Socarra, Dorotea Fantl, Guillermo J. Ruiz-Arguelles, Angelo Maiolino, Vania Tietsche de Moraes Hungria, Jean-Luc Harousseau, Brian Durie  Clinical Lymphoma, Myeloma and Leukemia  Volume 19, Issue 1, Pages e43-e50 (January 2019) DOI: /j.clml Copyright © 2018 Elsevier Inc. Terms and Conditions

2 Figure 1 Inquiry Flow Chart Displaying 16 Participating Active Countries From Latin American Clinical Lymphoma, Myeloma and Leukemia  , e43-e50DOI: ( /j.clml ) Copyright © 2018 Elsevier Inc. Terms and Conditions

3 Figure 2 Health Care Systems in Latin American Countries. Distribution of Health Care Systems, in Public Funded by Governments and Private by Supplemental Health Care Companies Among Latin American Countries Abbreviation: Dominican Rep = Dominican Republic. Clinical Lymphoma, Myeloma and Leukemia  , e43-e50DOI: ( /j.clml ) Copyright © 2018 Elsevier Inc. Terms and Conditions

4 Figure 3 First-line Multiple Myeloma Treatment for Elderly Patients Among Public and Private Health Systems in Latin American Countries in 2015 Abbreviations: CTD = cyclophosphamide, thalidomide, and dexamethasone; MPT = melphalan-prednisone and thalidomide; MTD = melphalan, thalidomide, and dexamethasone; RD = revlimid and dexamethasone; TD = thalidomide and dexamethasone; Vad-like = vincristine, adriamycin, and dexamethasone; VCD = velcade, cyclophosphamide, and dexamethasone; VD = velcade and dexamethasone; VTD = velcade, thalidomide, and dexamethasone. Clinical Lymphoma, Myeloma and Leukemia  , e43-e50DOI: ( /j.clml ) Copyright © 2018 Elsevier Inc. Terms and Conditions

5 Figure 4 First-line Multiple Myeloma Treatment for Transplant-eligible Patients Among Public and Private Health Systems in Latin American Countries in 2015 Abbreviations: CTD = cyclophosphamide, thalidomide, and dexamethasone; MPT = melphalan-prednisone and thalidomide; TD = thalidomide and dexamethasone; Vad = vincristine, Adriamycin, and dexamethasone; VCD = velcade, cyclophosphamide, and dexamethasone; VD = velcade and dexamethasone; VTD = velcade, thalidomide, and dexamethasone. Clinical Lymphoma, Myeloma and Leukemia  , e43-e50DOI: ( /j.clml ) Copyright © 2018 Elsevier Inc. Terms and Conditions

6 Figure 5 Challenges for LATAMC for Myeloma Drug Access in 2015 and Future: Main Problems and Possible Solutions. Summary of Main Barriers to Access of Anti-myeloma Drugs in Latin American Countries and Possible Solutions Abbreviations: Btz = bortezomib; CFZ = carfilzomib; Cy = cyclophosphamide; Dara = daratumumab; Elo = elotuzumab; ICER = The Institute for Clinical and Economical Review; Ixa = ixazomib; Len = lenalidomide; Mel = melphalan; Pan = panabinostat; POM = pomalidomide; Qalys = quality-adjusted life years; Thal = thalidomide; WHO = World Health Organization. Clinical Lymphoma, Myeloma and Leukemia  , e43-e50DOI: ( /j.clml ) Copyright © 2018 Elsevier Inc. Terms and Conditions


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