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Thymic Selection: To Thine Own Self Be True

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Presentation on theme: "Thymic Selection: To Thine Own Self Be True"— Presentation transcript:

1 Thymic Selection: To Thine Own Self Be True
Alexandra Kitz, David A. Hafler  Immunity  Volume 42, Issue 5, Pages (May 2015) DOI: /j.immuni Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Clonal Deletion Prunes the T Cell Repertoire without Eliminating Self-Reactive T Cells Self-reactive CD8 T cells can escape clonal deletion. Upon activation in the periphery, however, self-reactive T cells show a lower activation profile and a differential gene-expression pattern compared to foreign-reactive CD8 T cells. Immunity  , DOI: ( /j.immuni ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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