1. The Cell Cycle and Cell Division
What do these terms mean?

2. #1

11. Binary Fission and Mitosis Produce Genetically Identical Cells
In order for a cell to divide the following events must occur:
Reproductive signals
DNA replication
DNA segregation
Cytokinesis

12. Differences in Reproductive Signals
Binary Fission Mitosis #7

13. Differences in DNA Replication
Binary Fission Mitosis

14. Differences in DNA Segregation
Binary Fission Mitosis

15. Differences in Cytokinesis
Binary Fission Mitosis

17. Hypothetical Evolution of Mitosis
Since prokaryotes evolved before eukaryotes, mitosis probably evolved from binary fission.
Support: proteins involved in bacterial binary fission are related to the eukaryotic proteins that function in mitosis.

19. http://highered. mcgraw- hill. com/olcweb/cgi/pluginpop. cgi
hill.com/olcweb/cgi/pluginpop.cgi?it=swf::535::53 5::/sites/dl/free/ /120082/bio34a.swf: :Control%20of%20the%20Cell%20Cycle

23. PDGF Platelet derived growth factor: made by platelets
It is required for cell division of fibroblasts (connective tissue cell)
Have receptors on membrane that triggers a signal transduction pathway that allows the cell to pass G1 checkpoint.
Heals wound

24. Anchorage Dependence To divide they must be attached to a substratum.
Pathways involving plasma membrane proteins signal cell cycle.

25. Density Dependent Inhibition
External physical factor: crowded cells stop dividing because surface protein binds to neighbor and inhibits division