Presentation is loading. Please wait.

Presentation is loading. Please wait.

M.A.M. Rogers, D.M. Aronoff  Clinical Microbiology and Infection 

Similar presentations


Presentation on theme: "M.A.M. Rogers, D.M. Aronoff  Clinical Microbiology and Infection "— Presentation transcript:

1 The influence of non-steroidal anti-inflammatory drugs on the gut microbiome 
M.A.M. Rogers, D.M. Aronoff  Clinical Microbiology and Infection  Volume 22, Issue 2, Pages 178.e1-178.e9 (February 2016) DOI: /j.cmi Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Gut bacterial operational taxonomic units (OTUs) for participants using only one medication vs. participants using no medication. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Prevalence of gut bacterial families for participants using only non-steroidal anti-inflammatory drugs (NSAIDs) vs. participants not using medication. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4 Fig. 3 Receiver operating characteristic curves for participants using (a) non-steroidal anti-inflammatory drugs or (b) naproxen, showing discrimination by age, gender, and microbiome data. AUC, area under the curve. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

5 Fig. 4 Heat-map for bacterial families, showing differences in relative abundance by medication use. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

6 Fig. 5 Principal component analysis biplot of bacteria to distinguish ibuprofen users from naproxen users. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

7 Fig. 6 Relative abundance of bacterial operational taxonomic units (OTUs) by medication type. Abx, antibiotic; ATD, antidepressant; H2R, H2 receptor antagonist; Lax, laxative; NSAID, non-steroidal anti-inflammatory drug; PPI, proton-pump inhibitor. Clinical Microbiology and Infection  , 178.e1-178.e9DOI: ( /j.cmi ) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


Download ppt "M.A.M. Rogers, D.M. Aronoff  Clinical Microbiology and Infection "

Similar presentations


Ads by Google