1. Carbohydrate Maldigestion and Malabsorption
Anam Omer, Eamonn M.M. Quigley 
Clinical Gastroenterology and Hepatology 
Volume 16, Issue 8, Pages (August 2018)
DOI: /j.cgh
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2. Figure 1
In the small intestine the intraluminal phase of carbohydrate (CHO) digestion is accomplished primarily by pancreatic amylase, which generates disaccharides and monosaccharides. The mucosal phase, accomplished by brush-border enzymes, generates monosaccharides, which are transported across the enterocyte by specific transport mechanisms. Some of the latter are saturable and can in the face of excess dietary loads lead to more unabsorbed CHO. Unabsorbed CHO then reaches the colon, where bacterial metabolism generates lactic acid, SCFAs, and the gases hydrogen, methane, and carbon dioxide. Normally, most carbohydrates that reach the colon are salvaged in this way. Unabsorbed SCFAs stimulate colonic motility and secretion, leading to abdominal cramps and diarrhea; intraluminal gases may contribute to bloating, distention, and flatulence.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
Copyright © 2018 AGA Institute Terms and Conditions