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Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma  Annika Wallin, PhDa, Malcolm Sue-Chu, PhDb, Leif Bjermer,

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Presentation on theme: "Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma  Annika Wallin, PhDa, Malcolm Sue-Chu, PhDb, Leif Bjermer,"— Presentation transcript:

1 Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma 
Annika Wallin, PhDa, Malcolm Sue-Chu, PhDb, Leif Bjermer, MDc, Jonathan Ward, BScd, Thomas Sandström, MD, PhDa, Anne Lindberg, MDe, Bo Lundbäck, MD, PhDef, Ratko Djukanovic ́, DMd, Stephen Holgate, DScd, Susan Wilson, PhDd  Journal of Allergy and Clinical Immunology  Volume 112, Issue 1, Pages (July 2003) DOI: /mai Copyright © 2003 Mosby, Inc. Terms and Conditions

2 Fig. 1 Flow diagram indicating the total number of subjects randomized and the study inclusion criteria. The clinical characteristics for each treatment are summarized; the withdrawals within each group and total number of completed subjects are also given. All data are mean (± SE). *P < .05 compared with FP 400. Journal of Allergy and Clinical Immunology  , 72-78DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

3 Fig. 2 Graphs of clinical data depicting (A) FEV1, (B) morning PEF, and (C) evening PEF before and after each treatment. Significant differences are indicated. Journal of Allergy and Clinical Immunology  , 72-78DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

4 Fig. 3 Graph showing the number of (A) mast cells and (B) eosinophils in the submucosa. Significant changes are shown. These were the primary study end points. Journal of Allergy and Clinical Immunology  , 72-78DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions


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