Presentation is loading. Please wait.

Presentation is loading. Please wait.

Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between.

Published by Modified over 6 years ago

Similar presentations

Presentation on theme: "Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between."— Presentation transcript:

1 Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between Primary Non-small Cell Lung Cancer and Metastatic Lymph Nodes and the Significance in Mid- Term Survival  Chang Hyun Kang, MD, Bo Gun Jang, MD, Dong-Wan Kim, MD, Doo Hyun Chung, MD, Young Tae Kim, MD, Sanghoon Jheon, MD, Sook-Whan Sung, MD, Joo Hyun Kim, MD  Journal of Thoracic Oncology  Volume 4, Issue 11, Pages (November 2009) DOI: /JTO.0b013e3181b9f236 Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Immunohistochemical staining of (A) excision repair crosscomplementation group 1 (ERCC1), (B) x-ray repair crosscomplementation group 1 (XRCC1), and (C) βIII-tubulin. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181b9f236) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 A, Changes in excision repair crosscomplementation group 1 (ERCC1) expression in primary tumors and metastatic lymph nodes. B, Fifty-five percent of patients showed upregulation of metastatic lymph nodes, but downregulation was found in only 8% of patients. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181b9f236) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 A, Changes in x-ray repair crosscomplementation group 1 (XRCC1) expression in primary tumors and metastatic lymph nodes. B, Fifty-six percent of patients showed upregulation of XRCC1 expression, but only 6% of patients showed downregulation. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181b9f236) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 A, Changes in βIII-tubulin expression in primary tumor and metastatic lymph nodes. B, βIII-Tubulin expression in metastatic lymph nodes was downregulated in 45% of patients compared with 12% upregulation. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181b9f236) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

6 FIGURE 5 Overall survival according to the level of excision repair crosscomplementation group 1 (ERCC1) expression. A, Patients with upregulation of ERCC1 expression in N1 lymph nodes compared with the primary tumor site demonstrate significantly poor prognosis in N1 non-small cell lung cancer (p = 0.024). B, It shows survival curves according to ERCC1 up- or downregulation in N2 lymph nodes. However, the change in ERCC1 expression in N2 lymph node did not affect overall survival. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181b9f236) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

Download ppt "Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between."

Similar presentations

Massive Bronchogenic Cyst Joseph B. Levin, BA, Chi Wan Koo, MD, Jessica S. Donington, MD Journal of Thoracic Oncology Volume 5, Issue 11, Pages 1862-1863.

Massive Bronchogenic Cyst Joseph B. Levin, BA, Chi Wan Koo, MD, Jessica S. Donington, MD Journal of Thoracic Oncology Volume 5, Issue 11, Pages
The Accuracy of Frozen Section Diagnosis of Pulmonary Nodules: Evaluation of Inflation Method during Intraoperative Pathology Consultation with Cryosection.

The Accuracy of Frozen Section Diagnosis of Pulmonary Nodules: Evaluation of Inflation Method during Intraoperative Pathology Consultation with Cryosection.
Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between.

Differences in the Expression Profiles of Excision Repair Crosscomplementation Group 1, X-Ray Repair Crosscomplementation Group 1, and βIII-Tubulin Between.
Vascular endothelial growth factor expression in non-small-cell lung cancer: Prognostic significance in squamous cell carcinoma  Hideyuki Imoto, MD, Toshihiro.

Vascular endothelial growth factor expression in non-small-cell lung cancer: Prognostic significance in squamous cell carcinoma  Hideyuki Imoto, MD, Toshihiro.
Differences in Primary Care Clinicians' Approach to Non-small Cell Lung Cancer Patients Compared with Breast Cancer  Timothy R. Wassenaar, MD, Jens C.

Differences in Primary Care Clinicians' Approach to Non-small Cell Lung Cancer Patients Compared with Breast Cancer  Timothy R. Wassenaar, MD, Jens C.
Primary Mucoepidermoid Carcinoma of the Esophagus

Primary Mucoepidermoid Carcinoma of the Esophagus
Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.

Which is the Better Prognostic Factor for Resected Non-small Cell Lung Cancer: The Number of Metastatic Lymph Nodes or the Currently Used Nodal Stage.
Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.

Significance of the Number of Positive Lymph Nodes in Resected Non-small Cell Lung Cancer  Takayuki Fukui, MD, Shoichi Mori, MD, Kohei Yokoi, MD, Tetsuya.
Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer  Sai-Hong Ignatius Ou, MD, PhD, Jason.

Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer  Sai-Hong Ignatius Ou, MD, PhD, Jason.
A Novel Classification of MUC1 Expression Is Correlated with Tumor Differentiation and Postoperative Prognosis in Non–Small Cell Lung Cancer  Shinjiro.

A Novel Classification of MUC1 Expression Is Correlated with Tumor Differentiation and Postoperative Prognosis in Non–Small Cell Lung Cancer  Shinjiro.
The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR- Mutant Non–Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors 

The BIM Deletion Polymorphism and its Clinical Implication in Patients with EGFR- Mutant Non–Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors 
Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer  Seong Yong Park, MD, Hyun-Sung Lee, MD, PhD, Hee-Jin Jang, MD, Geon Kook.

Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer  Seong Yong Park, MD, Hyun-Sung Lee, MD, PhD, Hee-Jin Jang, MD, Geon Kook.
Susan C. Scott, MD, Nathan A. Pennell, MD, PhD 

Susan C. Scott, MD, Nathan A. Pennell, MD, PhD 
Ellen M. Schultz, MS, Gerard A. Silvestri, MD, MS, Michael K

Ellen M. Schultz, MS, Gerard A. Silvestri, MD, MS, Michael K
The Presence of Mutations in Epidermal Growth Factor Receptor Gene Is Not a Prognostic Factor for Long-Term Outcome after Surgical Resection of Non–Small-Cell.

The Presence of Mutations in Epidermal Growth Factor Receptor Gene Is Not a Prognostic Factor for Long-Term Outcome after Surgical Resection of Non–Small-Cell.
P2-090: Expression of cellular retinol binding protein-1 is associated with poor prognosis of stage I non-small cell lung cancer  Moo Suk Park, Yoon Soo.

P2-090: Expression of cellular retinol binding protein-1 is associated with poor prognosis of stage I non-small cell lung cancer  Moo Suk Park, Yoon Soo.
Difficulties in Diagnosis and Management of Ectopic Cushing Syndrome

Difficulties in Diagnosis and Management of Ectopic Cushing Syndrome
First-Line Gefitinib Treatment for Patients with Advanced Non-small Cell Lung Cancer with Poor Performance Status  Young Joo Lee, MD, Heung Tae Kim, MD,

First-Line Gefitinib Treatment for Patients with Advanced Non-small Cell Lung Cancer with Poor Performance Status  Young Joo Lee, MD, Heung Tae Kim, MD,
Lymph Node Ratio May Predict the Benefit of Postoperative Radiotherapy in Non– Small-Cell Lung Cancer  Damien Urban, MBBS, B Med Sc, Jair Bar, MD, PhD,

Lymph Node Ratio May Predict the Benefit of Postoperative Radiotherapy in Non– Small-Cell Lung Cancer  Damien Urban, MBBS, B Med Sc, Jair Bar, MD, PhD,
Prognostic Impact of Newly Proposed M Descriptors in TNM Classification of Non–Small Cell Lung Cancer  Junghoon Shin, MD, Bhumsuk Keam, MD, PhD, Miso.

Prognostic Impact of Newly Proposed M Descriptors in TNM Classification of Non–Small Cell Lung Cancer  Junghoon Shin, MD, Bhumsuk Keam, MD, PhD, Miso.

Similar presentations

Ads by Google