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Advanced Age and CV Risk: To Start or Not to Start a Statin in Older Patients?
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Definition of Elderly
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The Elderly and Vascular Disease
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Tailoring Lipid-Lowering Therapy in the Elderly
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Statins Highly Favorable Risk-Benefit Ratio
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Highest Risk of Statin Toxicity
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Polypharmacy and Drug-Drug Interactions
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Statin Pharmacokinetics
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Pitavastatin and Pravastatin: Less Likely to Interact With Common Medications in CV Care
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Common Drug Interactions With Statins
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PROSPER Study Design
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PROSPER Primary Endpoint
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Primary Prevention in the Elderly MI and Stroke Reduced With Statins
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JUPITER and HOPE-3 Trials
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STAREE STAtins for Reducing Events in the Elderly
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Secondary Prevention
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Secondary Prevention (cont)
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CTT Meta-Analysis
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Guideline Recommendations Statin Therapy in the Elderly (>75 Years)
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SCORE Cardiovascular Disease Risk Estimation
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REAL-CAD: Primary Endpoint CV Death/MI/Ischemic Stroke/Unstable Angina
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Nonadherence Is a Risk Factor for CV Events
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Reassuring the Patient About Statins
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2015 ACC Health Policy Statement Team Management
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Conclusion
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Abbreviations
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Abbreviations (cont)
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