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Subarachnoid Heamorrhage SAH
AHA & Piotr Szczudlik MD
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Nonaneurysmal causes of SAH 25%
Trauma Arteriovenous malformation Intracranial arterial dissection Cocaine and amphetamine use Mycotic aneurysm (septic) Central nervous system vasculitis Coagulation disorders
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Risk factors Hypertension OR-2,6 Smoking OR-2,2
High alcohol intake OR-1,5 First degree relatives Ehlers-Danlos, Marfan’s syndrome, pseudoxantoma elasticum, neurofibromatosis t. 1, polycystic kidney disease
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WFNS scale Grade 1 - Glasgow Coma Score (GCS) of 15, motor deficit absent Grade 2 - GCS of 13-14, motor deficit absent Grade 3 - GCS of 13-14, motor deficit present Grade 4 - GCS of 7-12, motor deficit absent or present Grade 5 - GCS of 3-6, motor deficit absent or present
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SAH is preceded in about 10% of the cases by a “sentinel headache”or warning leak, an episode of headache similar to that of SAH,and preceding it by days or weeks.
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Misdiagnosis 20 % !!!
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Perimesencephalic pattern of SAH
venous origin or due to intramural dissection benign course it can be complicated by hydrocephalus
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!!!! In 20-25% patients in acute stage the sight of bleeding will not be find in clasical arteriography (due to vasospasm, slot in aneurysm, and misinterpretation)
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Management protocol for acute SAH
Control elevated blood pressure to prevent rebleeding Intravenous hydration Check complete blood cell count, electrolytes (hyponatremia), CK-MB Vasospasm prophylaxis (nimodipine 60 mg p.o. every 4 hrs for 21 days)
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Triple H therapy Hypertension 160mmHg Haemodilution Hypervolaemia
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Recurrent Hemorrhage If the aneurysm is not treated, the risk
of rebleeding within 4 weeks is estimated to be of 35–40% After the first month the risk decreases gradually from 1–2%/day to 3%/year
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surgery vs endovascular
< 60 MCA wide neck of aneyrysm large ICH old age bad condition aneurysm in posterior localization (basilar artery)
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Asympyomatic Aneurysms
Contrary to current beliefs, aneurysms are not congenital but develop continuously during lifetime. Unruptured aneurysms have a risk of rupture of ~1%/year, depending on their size. Current evidence indicates that in patients with a life expectancy of at least 20 years, only those in the anterior circulation < 7mm should be left untreated. Screening for unruptured aneurysms is controversial.
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