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Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide  F.G. Araujo, T.L. Slifer, J.S. Remington  Clinical.

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Presentation on theme: "Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide  F.G. Araujo, T.L. Slifer, J.S. Remington  Clinical."— Presentation transcript:

1 Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide  F.G. Araujo, T.L. Slifer, J.S. Remington  Clinical Microbiology and Infection  Volume 8, Issue 1, Pages (January 2002) DOI: /j x Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

2 Figure 1 In vitro secretion of IL-1-α (a) and TNF-α (b) by LPS-stimulated or -unstimulated human monocytes at 3, 6 or 24 h. LPS stimulation resulted in a significant increase in the secretion of these cytokines by monocytes of all 10 donors. The figures show the combined results of monocytes from three representative donors. Clinical Microbiology and Infection 2002 8, 26-30DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

3 Figure 2 In vitro secretion of IL-1-α (a) and TNF-α (b) by human monocytes exposed for different time periods to LPS alone or to LPS plus different concentrations of moxifloxacin. Combined results of monocytes from the six responsive donors are shown. Clinical Microbiology and Infection 2002 8, 26-30DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions


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