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Metagenomics and development of the gut microbiota in infants

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1 Metagenomics and development of the gut microbiota in infants
Y. Valles, M.J. Gosalbes, L.E. de Vries, J.J. Abelián, M.P. Francino  Clinical Microbiology and Infection  Volume 18, Pages (July 2012) DOI: /j x Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 Histogram depicting the distribution of bacterial taxa of two meconium samples that were each separated into two parts: the external layers of the meconium (ME) and the internal part of the meconium (MI). Clinical Microbiology and Infection  , 21-26DOI: ( /j x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

3 FIG. 2 Heat-maps and sample clustering based on taxon (a) and function (b) frequencies detected in DNA metagenomic analyses. (a) Taxonomic assignments at genus level; only genera that have a proportion >I% in at least one sample are depicted. (b) Functional assignments based on the SEED functional classification [17]. Both taxonomic and functional assignments were obtained in the analysis platform MG-RAST (Metagenomics Rapid Annotation using Subsystem Technology: Heat-maps and clustering were obtained in R [18]. Clustering was based on the Bray-Curtis distance measure as implemented in the R package VEGAN. Colours in the figure depict the percentage range of sequences assigned to each genus or functional category. Clinical Microbiology and Infection  , 21-26DOI: ( /j x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions


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