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Goserelin Acetate (Zoladex)∗with or without Hormone Replacement Therapy for the Treatment of Endometriosis  Kamran S Moghissi, M.D., William D Schlaff,

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Presentation on theme: "Goserelin Acetate (Zoladex)∗with or without Hormone Replacement Therapy for the Treatment of Endometriosis  Kamran S Moghissi, M.D., William D Schlaff,"— Presentation transcript:

1 Goserelin Acetate (Zoladex)∗with or without Hormone Replacement Therapy for the Treatment of Endometriosis  Kamran S Moghissi, M.D., William D Schlaff, M.D., David L Olive, M.D., Michael A Skinner, B.S., Helen Yin, M.S.  Fertility and Sterility  Volume 69, Issue 6, Pages (June 1998) DOI: /S (98)

2 FIGURE 1 Mean values for total pelvic symptom score. The decrease in total pelvic symptom score was significantly (P =.011) greater for HRT1 than for the HRT0 or HRT2 at week 12 and significantly (P =.003) less for HRT2 than HRT0 or HRT1 at week 16. Fertility and Sterility  , DOI: ( /S (98) )

3 FIGURE 2 Mean values for total subjective symptom score.
Fertility and Sterility  , DOI: ( /S (98) )

4 FIGURE 3 Mean value of bone mineral density.
Fertility and Sterility  , DOI: ( /S (98) )

5 FIGURE 4 Mean intensity scores for physiologic side effects of goserelin treatment: (A), Vaginal dryness. (B), Hot flushes. The difference in the mean score as for the HRT1 and HRT2 groups versus the HRT0 group was statistically significant for hot flushes (P <.001) at weeks 12 and 24 and for vaginal dryness (P = .007) at week 24. Fertility and Sterility  , DOI: ( /S (98) )


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