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Farah Parveen, M.Sc., Anju Shukla, M.D., Suraksha Agarwal, Ph.D. 

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Presentation on theme: "Farah Parveen, M.Sc., Anju Shukla, M.D., Suraksha Agarwal, Ph.D. "— Presentation transcript:

1 Cytokine gene polymorphisms in northern Indian women with recurrent miscarriages 
Farah Parveen, M.Sc., Anju Shukla, M.D., Suraksha Agarwal, Ph.D.  Fertility and Sterility  Volume 99, Issue 2, Pages e2 (February 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Meta-analysis of (A) interleukin (IL) 6, (B) IL-10 (1082), and (C) interferon-γ. Odds ratio estimates with 95% confidence interval (CI), random-effect model. The size of the square is proportional to the percentage weight of each study; horizontal lines represent 95% CI. Fertility and Sterility  , e2DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Classification and regression tree analysis analysis of genetic variants of proinflammatory and antiinflammatory pathway genes in modulating recurrent miscarriage risk. Mother node constitutes interleukin (IL) A/T divided into two nodes: mutant and heterozygous (mutant and wild type). Wild type is attached to IL-1 RN8006 heteromutant and wild node is attached to IL-4 590C/T. This pathway, i.e., IL-10–IL-1–IL-4 is the protective pathway with moderate OR. Fertility and Sterility  , e2DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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