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Here is chronic endometritis with lymphocytes and plasma cells in the endometrial stroma. In general, the inflammatory infiltrate of chronic inflammation.

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Presentation on theme: "Here is chronic endometritis with lymphocytes and plasma cells in the endometrial stroma. In general, the inflammatory infiltrate of chronic inflammation."— Presentation transcript:

1 Here is chronic endometritis with lymphocytes and plasma cells in the endometrial stroma. In general, the inflammatory infiltrate of chronic inflammation consists mainly of mononuclear cells: lymphocytes, plasma cells, and macrophages.

2 Chronic cervicitis. Prolonged acute inflammation or repeated bout of acute inflammation may lead to the presence of more mononuclear cells and chronic inflammation with fibrosis.

3 chronic inflammation due to hypersensitivity reaction: Nasal mass with edematous stroma with chronic inflammatory cell infiltrate ( mainly eosinophils) covered by ciliated columnar epithelium allergic nasal polyp

4 Grossly, a granuloma tends to be a focal lesion
Grossly, a granuloma tends to be a focal lesion. Seen here in a hilar lymph node replaced by cheesy white material of caseous necrosis. Diagnosis: Granuloma with caseous necrosis (cheesy- like white material)

5 Microscopic section of lung in which there are scattered granulomas in the parenchyma composed of epitheloid cells surrounded by lymphocytes with multiple giant cells

6 Here are two pulmonary granulomas
Here are two pulmonary granulomas. Granulomatous inflammation typically consists of epithelioid macrophages, giant cells, lymphocytes, plasma cells, and fibroblasts. There may be some neutrophils.

7 Here is a foreign body type giant cell at the upper left of center adjacent to a segment of vegetable material aspirated into the lung. Such foreign body giant cells have nuclei scattered haphazardly about the cell. Diagnosis: foreign body granuloma.

8 Two foreign body giant cells are seen just to the right of center where there is a bluish strand of suture material from a previous operation. Diagnosis: foreign body giant cells

9 Two large granulomas composed of epithelioid macrophages surrounded by lymphocytes showing two Langhans type giant cells in which the nuclei are lined up around the periphery of the cell. Diagnosis: granulomatous disease

10 This is a caseating granuloma
This is a caseating granuloma. Epithelioid cells surround a central area of necrosis that appears irregular, amorphous, and pink. Diagnosis: caseating granuloma ( mostly T.B.).


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